Four-Body Scoring Function for Mutagenesis

Paper (accepted in Bioinformatics)                      best viewed using Acrobat Reader
Supplement: Description of Data Set of Mutants

List of all mutations (ordered the same way as Table 1 in the paper) - Excel file     HTML file

Other data sets of mutants scored

• Sets of 1096 (training) and 388 (test) single-point mutants studied by Cheng et al.
• Outlier mutants studied by Guerois et al.
• Our list of mutants scored using the FOLD-X energy function (Guerois et al.)
• T4 Lysozyme mutants studied by Topham et al.

Excecutable programs (compiled using gcc version 3.3.3 20040412 (Red Hat Linux 3.3.3-7):

• MultiMutate.exe
• CombinatorialMutate.exe
• Readme_MultiMutate.txt - instructions for running the programs.
  Files mentioned in Readme: list_mutate.txt and input_comb.txt;   
  Mutants_1ERXA_6.txt, Mutants_2CI2I_5.txt, and Mutants_2ACY__12.txt.