Scoring Function to Predict Solubility Mutagenesis

Paper (pdf)

List of all mutations (ordered the same way as Table 1 in the paper) - SolMut_Dataset.xls
Input files (with all 137 mutants) for use with the program: input_mutpdbs.txt    input_listmuts.txt

Confusion matrices for all predictions.

Cross validation across sequentially diverse folds, and average hydrophobicity calculations:

Script files to draw triangles in VMD for 1VQB.pdb and 2ACY.pdb: 1vqb_9A_triangles.txt    2acy_9A_triangles.txt
    (Load the PDB file into VMD, and then play the corresponding script file.)

Excecutable programs

Bala Krishnamoorthy
Last modified: Wed Oct 6 14:09:40 PDT 2010