Edward Pate

Modelling $\bullet$ Biomathematics

1. X-ray structures of the Dictyostelium discoideum myosin motor domain with six non-nucleotide analogs, (with A.M. Gulick, C.B. Bauer, J.B. Thoden, R.G. Yount and I. Rayment), J. Biol. Chem, 275 (2000), 398-408.

2. Synthesis and characterization of novel spin-labeled photoaffinity non-nucleoside analogs of ATP as structural and EPR probes for myosin, (with X. Chen, J. Grammer, R. Cooke, and R.G. Yount), Bioconj. Chem, 11 (2000), 725-733.

3. Molecular dynamics analysis of the structural, mechanistic, and energetic implications of switch 1 movements in ncd, (with T.J. Minehardt, R. Cooke and P.A. Kollman), Biophys. J., 80 (2000), 1151-1181.

4. A classical and ab-intio study of the interaction of the myosin tripho pleate binding domain, (with *Minehardt, T.J., Cooke, R., Pate, E., and Car, R.) Biophys. J., 82 (2002), 660-675.

5. A novel restricted photoaffinity spin-labeled non-nucleoside ATP analog as a coralenty attached reporter group of the active site of myosin, (with *Chen, X., Grammer, J., Lawson, J.D., Cooke, R., Pate, E., and Yount, R.G.) Biochemistry, 41 (2002), 2609-2620.

6. EPR spectroscopy shows a microtubule-dependent conformational change in the switch 1 domain of kinesin (with Naber, N., Rice, S., Matuska, N.M., Vale, R.D. and R. Cooke), Biophys. J. 84: (2003), 3190-3196.

7. Closing of the nucleotide pocket of kinesin-family motors uponbinging to microtubules (with Naber, N., Minehardt, T.J., Rice, Chen, X, Grammer, J., Vale, R.D., Kollman, P.A., Yount, R.G., and R. Cooke), Science 300 (2003), 798-801

8. Molecular dynamics of structural factors influencing "back door" phosphate release in myosin (with Lawson, J.D., Rayment, I., and Yount, R.G.) Biophys. J. 86 (2004), 3794-3803.